Many people believe, that the flu does not differ from the majority of colds. In fact, this pathology can be very dangerous, especially if you treat it properly. Influenza Therapy should include antivirals, one of which is Amizon.
This tool is suitable for children and adults. In a review of doctors notes, that effect is often dependent on the stage of disease in man and individual resistance to the active substance. The rest of the, responses to the drug doctors say Amizon ability means to accelerate the healing process and reduce the chance of complications.
Release form and composition
Amizon tablets - a round capsule, painted in green or yellow, Sheathed. They are packaged on blisters, each of which is ten pieces. Packaging produced in two versions. The first contains one blister, and the other two. Thus in the box may be ten to twenty tablets.
Active component of the composition is amizon, also called enisamium iodide. This derivative of isonicotinic acid. The concentration of active substance varies depending on the form of preparation.
note. There is a children's Amizon, In this case, the tablets are manufactured by 0,125 g. They were allowed to take between six and twelve years old.
Capsules for adults contain 250 mg of active ingredient. In both cases, adjuvants are:
- Microcrystalline cellulose,
- croscarmellose sodium,
- lactose monohydrate,
- povidone,
- calcium stearate
- low molecular weight polyvinylpyrrolidone,
- Potato starch.
In preparation Max Amizon instruction indicates a similar composition. Each capsule is present 0,5 g enisamiuma iodide, and the additional element is magnesium stearate. Gelatin capsules are gelatin their, titanium dioxide and a yellow-orange dye. In addition to the tablet form, issued Amizonchik medicine (or Amizon Kids), This syrup for children. It includes:
- 10 enisamiuma mg iodide per milliliter of syrup,
- Didekagidrat,
- Lemon acid,
- sodium phosphate,
- Purified water,
- sorbitol solution,
- flavors.
Regardless of the form of release of the drug, everywhere the active ingredient is used the same, its concentration varies only. Enisamium iodide inhibits the activity of influenza viruses, It has interferonogenic impact and enhances the human body's resistance to various infections. The substance is an analgesic, antipyretic and anti-inflammatory effect.
Pharmacodynamics and pharmacokinetics
Amizona components reduce inflammation due to the effect on the lysosomal membrane, and cell. They inhibit the destruction of the basophil granules, one of the subtypes of white blood cells, which are very important for the immune system. Substances have antioxidant effect and normalize the amount of prostaglandins, are involved in the relaxation of muscles and reducing the gastrointestinal tract, slow down platelet aggregation.
The anti-inflammatory properties are also caused by the fact, that the drug affects the energy metabolism at the site of inflammation and reduces the degree of reaction vessels. Antipyretic effect is due to effects on the brain centers, responsible for thermoregulation. Pain relief is due to effects on the central parts of the spinal cord and brain stem, which consist of a reticular nuclei.
note. The drug reduces disease duration.
Receiving Amizona approximately fourfold increases in the plasma levels of endogenous interferon and facilitates the work of macrophages and T-lymphocytes. As a result, there is a strengthening of the humoral and cellular immunity. Body resistance is improved by increasing the level of lysozyme, enzyme, Bacteria can destroy the wall.
After consumption of the drug ingredients quickly into the blood. Their maximum concentration seen after about two hours from the time of reception. For blood half-life of the process requires about fourteen hours, but most tissues the drug is derived has three hours. It goes almost entirely from the body as metabolites by the kidneys.
Indications
Most often Amizon prescribed for treatment and prevention of diseases such as influenza. These include rhinovirus and adenovirus infection, and parainfluenza. The medicine for children, that long can not get better or get sick often. In addition to respiratory infections, instructions for use Amizona allows its use against bacterial, viral and viral-bacterial pathologies, such as infectious mononucleosis, tonsillitis and pneumonia.
Other indications are the use:
- Rubella,
- Measles,
- Chickenpox,
- Parotitnaya infection,
- scarlet fever,
- Cat scratch disease,
- pseudoerysipelas (skin-articular form).
Sometimes prescribed drug as a preventive agent, if there were pockets of hepatitis A and E infections. Amizon can serve an additional measure effects in the treatment of several diseases. Firstly, This variety of forms of meningitis, and chronic brucellosis, typhoid fever.
Means used in the treatment of herpetic infections and keratitis, keratokonayunktivitov, posterior and anterior uveitis. It is used in the treatment of intervertebral hernia, neuralgia, arthritis and degenerative disc disease. Sometimes Amizon protrudes auxiliary component in influencing inflammatory processes, related to gynecology and obstetrics.
Contraindications and side effects
Instructions to Amizon prohibits the use of the drug, if there is a sensitivity to iodine or any other component of the formulation. It can not be used in the first trimester of childbearing, and it is not suitable for children younger than six years. Amizon contraindicated in serious liver and kidney diseases.
There are the following side effects:
- allergic reactions. There is itching and skin rashes, possible urticaria and angioedema.
- Disorders of the digestive system. This includes abdominal pain, nausea and vomiting, increased salivation, izzhogu, tongue discoloration, appearance of bitterness in the mouth, the swelling of the mucous of the oral cavity, inflation, diarrhea and heaviness in the right upper quadrant.
- Problems with the respiratory system. Possible irritation of the throat and shortness of breath.
Occasionally, some patients experienced headache and dizziness, loss of strength and changes in blood pressure. Most often side effects have evolved against a background of non-compliance of the drug. Treatment of overdose associated with the elimination of any symptoms, can be carried out gastric lavage.
How to take Amizon?
Guide to the use of pills recommended to drink after a meal. The amount of drug and length of treatment depend on the particular disease. The following options are common dosages:
- For the treatment of respiratory disorders adults appoint 250-500 mg up to four times a day for a week. Children over six years prescribed by 125 mg three times a day.
- Against meningitis and encephalitis drink 250 mg for ten days three times a day.
- The same number is used against epidparotita, week duration of therapy is. For the prevention of just two doses per day.
- chickenpox, rubella and measles for children older than six given by 125 mg three times a day, older than eight - four times. If the child is over the age of twelve, it may take 250 mg three times a day. The adult dosage is 500 mg three times a day.
- three-time reception 125 mg is used for the treatment of mononucleosis. The amount may be increased in severe.
Treat pseudoerysipelas using Amizona Only adults. They should drink 500 mg of the drug twice a day for two weeks. As prophylaxis of hepatitis take 250 mg three times a day. Against angina of moderate severity drink 250 mg up to four times a day, and in severe - thrice 500 mg.
Cost and analogues
Buy Amizon can be as low as 300 to 500 rubles. The cost of the syrup is generally in the area 350-400 rubles. To him you can pick up cheap analogues, drugs which are presented like Panavir, Arbidol and Arpeflyu. average cost (about 200 rubles) It will have Jodantipyrin and Kagocel.
In preparation Amizon analogues with similar effects are represented tablets Engystol, Flavozid, Altabor and Mangogerpin. You can also buy drugs such Armenikuma, Imustata, Novirina, Groprinozina and Amidopirina. From the viewpoint of the analgesic properties, Amizon similar analginum, but from the point of view of antipyretic ibuprofen.
